Considerations To Know About ceesdekker
Considerations To Know About ceesdekker
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Rotary movement of DNA rotors on nanopores. Prime row: raw movie from the Cy5 channel of each and every rotor. Center row: corresponding single-particle localization success of equally ends on the DNA rotors. The position of the present frame is marked as orange and blue dots, as well as trajectory of the 10 frames right before The present body is proven as solid traces.
Human Rad51 filaments on double- and one-stranded DNA: correlating typical and irregular sorts with recombination function.
Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins
2007, initial true-time detection of strand Trade in homologous recombination by RecA; discovery of a lower persistence duration of ends of microtubules; and settled the system of biosensing with carbon nanotubes
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Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes
Considering that 2000 he moved to single-molecule biophysics and nanobiology, with research from DNA supercoiling experiments of nucleosomes and DNA mend proteins to DNA translocation by means of nanopores. Lately his research has centered on learning mobile division with microbes on chip, although his ultimate curiosity is in the course of noticing synthetic cells.
Nanopores symbolize an elegant and flexible Instrument to measure one molecules. We investigate novel detection modes with good-point out nanopores and many tips on how to evaluate proteins with nanopores. Assignments encompass the next:
What if, in lieu of employing conventional top rated-down silicon electronics, transistors might be crafted from the bottom up working with single natural and organic molecules because the switching elements? This concept, which turned the basis of currently’s area of molecular electronics, initially emerged within the seventies.
It was throughout this period that Dekker carried out analysis on magnetic spin programs and on sound in superconductors and semiconductors.
Screening pseudotopological and nontopological styles for SMC-driven DNA loop extrusion towards roadblock-traversal experiments
1999, to start with measurement in the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for the new Luttinger description of interacting electrons in nanotubes
2008, initially observation of protein-coated DNA translocation by nanopores; solved the origin on the electrophoretic https://www.ceesdekker.net power on DNA in nanopores; found a substantial velocity increase of microtubules in electric powered fields; found out an anomalous electro-hydrodynamic orientation of microtubules; and solved the origin of sound in carbon nanotubes in liquid
2004, discovery of recent physics in translocation of DNA by way of nanopores; initial experimental analyze of ions conduction in nanofluidic channels; 1st electrochemistry with person one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; initially electrical docking of microtubules on kinesin-coated nanostructures; very first biophysics characterization of the mechanical Houses of double-stranded RNA; and initial one-molecule research of DNA translocation by a restriction-modification enzyme.